Diana M Downs Selected Research

Imines

1/2022	2-Aminoacrylate stress damages diverse PLP-dependent enzymes in vivo.
12/2021	Absence of MMF1 disrupts heme biosynthesis by targeting Hem1pin Saccharomyces cerevisiae.
1/2021	The Rid family member RutC of Escherichia coli is a 3-aminoacrylate deaminase.
1/2020	RidA Proteins Protect against Metabolic Damage by Reactive Intermediates.
10/2019	Reactive Enamines and Imines In Vivo: Lessons from the RidA Paradigm.
1/2018	Mmf1p Couples Amino Acid Metabolism to Mitochondrial DNA Maintenance in Saccharomyces cerevisiae.
1/2017	Members of the Rid protein family have broad imine deaminase activity and can accelerate the Pseudomonas aeruginosa D-arginine dehydrogenase (DauA) reaction in vitro.
1/2016	2-Aminoacrylate Stress Induces a Context-Dependent Glycine Requirement in ridA Strains of Salmonella enterica.
5/2015	Genomic and experimental evidence for multiple metabolic functions in the RidA/YjgF/YER057c/UK114 (Rid) protein family.
9/2014	Endogenous synthesis of 2-aminoacrylate contributes to cysteine sensitivity in Salmonella enterica.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Diana M Downs Research Topics

Disease

29	Scrapie 01/2022 - 01/2012
1	Vitamin B 6 Deficiency (Pyridoxine Deficiency) 01/2022
1	Protein Deficiency 01/2022
1	Infections 11/2020
1	Carcinogenesis 01/2020
1	Epilepsy (Aura) 01/2019
1	Hypersensitivity (Allergy) 10/2016
1	Neoplasms (Cancer) 04/2015
1	Dehydration (Water Stress) 09/2014
1	Iron Deficiencies 12/2008

Drug/Important Bio-Agent (IBA)

23	Proteins (Proteins, Gene)FDA Link 12/2021 - 01/2012
21	EnzymesIBA 01/2022 - 01/2013
13	IminesIBA 01/2022 - 01/2012
13	PyridoxalIBA 01/2022 - 08/2013
4	Threonine (L-Threonine)FDA Link 01/2022 - 01/2012
4	Serine (L-Serine)FDA Link 01/2022 - 01/2012
3	Glycine Hydroxymethyltransferase (Serine Hydroxymethyltransferase)IBA 03/2020 - 08/2013
3	Branched-Chain Amino AcidsIBA 12/2019 - 02/2013
3	Pyruvic Acid (Pyruvate)IBA 01/2018 - 08/2013
3	Hydro-Lyases (Dehydratases)IBA 09/2014 - 02/2013
2	L-Serine Dehydratase (Serine Dehydratase)IBA 01/2022 - 02/2013
2	Amino Acids FDA Link 01/2020 - 05/2015
1	Isoleucine (L-Isoleucine)FDA Link 01/2022
1	cysteine desulfuraseIBA 01/2022
1	Vitamin B 6IBA 01/2022
1	Pyridoxine (Pyridoxin)FDA LinkGeneric 01/2022
1	Glucose (Dextrose)FDA LinkGeneric 01/2022
1	NAD (NADH)IBA 01/2022
1	Mitochondrial DNA (mtDNA)IBA 12/2021
1	Aromatic Amino Acids (Aromatic Amino Acid)IBA 11/2020
1	Protons (Proton)IBA 03/2020
1	Pyridoxal Phosphate (Pyridoxal 5 Phosphate)IBA 01/2020
1	Folic Acid (Vitamin M)FDA LinkGeneric 12/2019
1	KetonesIBA 10/2019
1	Biological ProductsIBA 10/2019
1	VitaminsIBA 01/2019
1	Methionine (L-Methionine)FDA Link 01/2018
1	Complement System Proteins (Complement)IBA 01/2018
1	CystathionineIBA 01/2018
1	glutamate racemaseIBA 01/2018
1	LyasesIBA 01/2018
1	Aspartic Acid (Aspartate)FDA Link 01/2018
1	arginine oxidaseIBA 01/2017
1	AllergensIBA 10/2016
1	RNA (Ribonucleic Acid)IBA 01/2016
1	CarbonIBA 01/2016
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2016
1	Oxidoreductases (Dehydrogenase)IBA 05/2015
1	4,5-dihydroorotic acidIBA 05/2015
1	Carbamyl Phosphate (Carbamoyl Phosphate)IBA 05/2015
1	Arginine (L-Arginine)FDA Link 05/2015
1	Threonine Dehydratase (Threonine Ammonia-Lyase)IBA 05/2015
1	HydrolasesIBA 05/2015
1	AminesIBA 05/2015
1	Reactive Nitrogen SpeciesIBA 04/2015
1	AcidsIBA 09/2014
1	Cysteine (L-Cysteine)FDA Link 09/2014
1	Cystathionine gamma-Lyase (Cysteine Desulfhydrase)IBA 09/2014
1	Green Fluorescent ProteinsIBA 07/2014
1	Transaminases (Aminotransferases)IBA 07/2014
1	preemptIBA 07/2014
1	Racemases and Epimerases (Epimerases and Racemases)IBA 08/2013
1	Alanine (L-Alanine)FDA Link 08/2013
1	Coenzyme A (CoA)IBA 08/2013
1	Alanine RacemaseIBA 08/2013
1	branched-chain-amino-acid transaminaseIBA 02/2013
1	Keto AcidsIBA 02/2013
1	4-hydroxy-tetrahydrodipicolinate synthase (dihydrodipicolinate synthase)IBA 01/2012
1	Homoserine DehydrogenaseIBA 01/2012
1	Reducing AgentsIBA 12/2008
1	Glutathione (Reduced Glutathione)IBA 12/2008